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National MS Society announces grants
By Pamela Glason Thornton
Staff Writer
Columbus Post
With the addition of $777,899 for two MS-related research projects, a total of $7.8 million in research dollars is being spent in Ohio to help find the cause and cure for the unpredictable disease of the central nervous system.
Grants have been awarded to two researchers from The Ohio State University (OSU): Xue-Feng Bai, M.D., Ph.D., from the Department of Pathology in the School of Medicine and Caroline Whitacre, Ph.D., of the College of Medicine and Public Health.
Bai will receive $272,953 for his project on the CD24 gene and experimental autoimmune encephalomyelitis (EAE).
Whitacre will use $504,946 to study the migration inhibitory factor (MIF) in the progression of EAE.
According to Kottil Rammohan, M.D., Director of the Multiple Sclerosis Center and Neuroimmunology Laboratory at OSU and Chair of the Society’s Clinical Advisory Committee, Dr. Bai is working with Dr. Yang Liu to learn crucial information on the role of the CD24 gene in humans. The doctors are studying how changes in the gene correlate with differences in susceptibility or disorder resistance.
"Their observations in mice have been extended to patients with multiple sclerosis which makes the study of the genetics of EAE in mice very important," said Dr. Rammohan.
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